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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF4
All Species:
23.64
Human Site:
Y172
Identified Species:
47.27
UniProt:
Q8IWZ8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWZ8
NP_757386.2
645
72471
Y172
D
E
D
E
E
E
D
Y
E
Q
W
L
E
I
K
Chimpanzee
Pan troglodytes
XP_001142356
641
71959
Y168
D
E
D
E
E
E
D
Y
E
Q
W
L
E
I
K
Rhesus Macaque
Macaca mulatta
XP_001115248
641
72031
Y168
D
E
D
E
E
E
D
Y
E
Q
W
L
E
I
K
Dog
Lupus familis
XP_533865
628
70914
Y159
D
E
D
E
E
E
D
Y
E
Q
W
L
E
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CH02
643
72631
Y168
D
D
D
E
E
E
D
Y
E
Q
W
L
E
I
K
Rat
Rattus norvegicus
Q68FU8
644
72577
D168
D
D
D
D
E
E
E
D
Y
E
Q
W
L
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518067
230
26983
Chicken
Gallus gallus
XP_425909
649
73577
Y174
D
E
D
E
E
E
D
Y
E
Q
W
L
E
I
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730937
832
93822
Q237
G
L
P
V
Q
A
V
Q
P
P
P
P
P
P
F
Honey Bee
Apis mellifera
XP_393042
903
98662
S369
S
S
N
Q
L
P
L
S
S
L
S
S
T
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788058
434
48257
Q19
G
P
I
K
P
S
F
Q
D
K
M
K
S
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94C11
443
48675
D28
R
Q
L
Q
Q
E
K
D
K
D
K
D
K
V
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.1
89.7
N.A.
89.6
89.3
N.A.
34.1
75.9
N.A.
N.A.
N.A.
25.2
25.1
N.A.
33.9
Protein Similarity:
100
99.2
98.7
91.7
N.A.
94.4
93.8
N.A.
35.1
84.1
N.A.
N.A.
N.A.
39.9
39.2
N.A.
45.8
P-Site Identity:
100
100
100
100
N.A.
93.3
26.6
N.A.
0
100
N.A.
N.A.
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
53.3
N.A.
0
100
N.A.
N.A.
N.A.
6.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
59
17
59
9
0
0
50
17
9
9
0
9
0
0
0
% D
% Glu:
0
42
0
50
59
67
9
0
50
9
0
0
50
9
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% F
% Gly:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
50
9
% I
% Lys:
0
0
0
9
0
0
9
0
9
9
9
9
9
0
50
% K
% Leu:
0
9
9
0
9
0
9
0
0
9
0
50
9
17
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
9
0
9
9
0
0
9
9
9
9
9
9
0
% P
% Gln:
0
9
0
17
17
0
0
17
0
50
9
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
0
0
0
9
0
9
9
0
9
9
9
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
0
9
0
0
9
0
0
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
50
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _